The IFNGR2 Antibody (CAB7558) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By targeting the IFNGR2 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in immunology, infectious diseases, and cancer research.IFNGR2, also known as interferon gamma receptor 2, plays a crucial role in mediating the effects of interferon-gamma, a key cytokine involved in immune responses.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
IFNGR2 Antibody
SKU:
CAB7558
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
KDSS PKDD VWDS VSI
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AF-1, IFGR2, IMD28, IFNGT1, IFNGR2
Positive Sample:
HeLa, F9
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
38kDa
Observed MW:
38kDa
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Purification Method
Affinity purification
Gene ID
3460
RRID
AB_2768083
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using IFNGR2 Rabbit pAb (CAB7558) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
