The IL1R1 Antibody (CAB5727) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.IL1R1, also known as interleukin-1 receptor type 1, plays a crucial role in mediating the effects of interleukin-1, a key pro-inflammatory cytokine. By binding to IL1R1, researchers can detect and analyze the protein in various cell types, providing insights into the mechanisms of immune signaling and inflammatory processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
IL1R1 Antibody
SKU:
CAB5727
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Cell Membrane, Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:
65kDa
Observed MW:
80kDa
This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
Purification Method
Affinity purification
Gene ID
3554
RRID
AB_2766484
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse liver, using IL1R1 Rabbit pAb (CAB5727) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
