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Anti-IL-6 Antibody (CAB11114)

SKU:
CAB11114
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-IL-6 Antibody CAB11114
  • Immunology Antibodies 1 Anti-IL-6 Antibody CAB11114
  • Immunology Antibodies 1 Anti-IL-6 Antibody CAB11114
$167 - $503
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Description

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Antibody Name:IL6 Rabbit Polyclonal Antibody
Antibody SKU:CAB11114
Antibody Size:20uL, 50uL, 100uL
Application:IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human IL6 (NP_000591.1).
Application:IHC
Recommended Dilution:IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human IL6 (NP_000591.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VPPG EDSK DVAA PHRQ PLTS SERI DKQI RYIL DGIS ALRK ETCN KSNM CESS KEAL AENN LNLP KMAE KDGC FQSG FNEE TCLV KIIT GLLE FEVY LEYL QNRF ESSE EQAR AVQM STKV LIQF LQKK AKNL DAIT TPDP TTNA SLLT KLQA QNQW LQDM TTHL ILRS FKEF LQSS LRAL RQM
Gene ID:3569
Uniprot:P05231
Cellular Location:Secreted
Calculated MW:23kDa
Observed MW:
Synonyms:IL6, BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6
Background:This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
UniProt Code:P05231
NCBI GenInfo Identifier:124347
NCBI Gene ID:3569
NCBI Accession:P05231.1
UniProt Secondary Accession:P05231,Q9UCU2, Q9UCU3, Q9UCU4,
UniProt Related Accession:P05231
Molecular Weight:212
NCBI Full Name:Interleukin-6
NCBI Synonym Full Names:interleukin 6
NCBI Official Symbol:IL6  
NCBI Official Synonym Symbols:HGF; HSF; BSF2; IL-6; IFNB2  
NCBI Protein Information:interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor
UniProt Protein Name:Interleukin-6
UniProt Synonym Protein Names:B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
Protein Family:Interleukin
UniProt Gene Name:IL6  
UniProt Entry Name:IL6_HUMAN
Anti-IL-6 Antibody (CAB11114)Immunohistochemistry of paraffin-embedded rat brain using IL6 antibody (CAB11114) at dilution of 1:100 (40x lens).
Anti-IL-6 Antibody (CAB11114)Immunohistochemistry of paraffin-embedded human esophagus using IL6 antibody (CAB11114) at dilution of 1:100 (40x lens).
Anti-IL-6 Antibody (CAB11114)Immunohistochemistry of paraffin-embedded mouse stomach using IL6 antibody (CAB11114) at dilution of 1:100 (40x lens).

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