The IRAK3 Antibody (CAB13402) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to IRAK3, this antibody enables accurate detection and analysis of the protein in a variety of cell types.IRAK3, also known as interleukin-1 receptor-associated kinase 3, plays a key role in regulating the immune response and inflammatory signaling pathways. Dysregulation of IRAK3 has been linked to various immune-related disorders, making it a promising target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
IRAK3 Antibody
SKU:
CAB13402
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ASRT5, IRAKM, IRAK3
Positive Sample:
HL-60, THP-1, Mouse lung, Rat lung
Cellular Localization:
Cytoplasm, Nucleus, Plasma Membrane.
Calculated MW:
68kDa
Observed MW:
68kDa
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
11213
RRID
AB_2760263
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IRAK3 Rabbit pAb (CAB13402) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
