The gamma-Catenin Antibody (CAB0963) is a high-quality antibody developed for reliable detection and analysis of target proteins. JUP is a key component of cell-cell adhesion complexes and is involved in maintaining tissue integrity and signaling pathways in various cell types.This antibody, generated in rabbits, is highly specific to JUP in human samples and has been validated for use in Western blot applications. By binding to JUP, researchers can detect and analyze the protein in different cell types, making it ideal for studies in cell biology, developmental biology, and cancer research.
This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
gamma-Catenin Antibody
SKU:
CAB0963
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Purification Method
Affinity purification
Gene ID
3728
RRID
AB_2757484
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using γ-Catenin Rabbit pAb (CAB0963) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020).
Immunoprecipitation analysis of 200 μg extracts of MCF-7 cells, using 3 μg γ-Catenin antibody (CAB0963). Western blot was performed from the immunoprecipitate using γ-Catenin antibody (CAB0963) at a dilution of 1:1000.
