The KO Validated AES Rabbit Polyclonal Antibody (CAB19944) is a specialized antibody developed for researchers studying CD300A, a crucial cell surface molecule involved in immune regulation. With its ability to inhibit immune responses, CD300A is a key target for investigations in immunology and cancer research.This antibody, raised in rabbits, offers high reactivity with human samples and has been rigorously validated for Western blot applications. By specifically binding to the CD300A protein, researchers can effectively detect and analyze this molecule in various cell types, providing valuable insights into immune modulation and potential therapeutic targets.
The importance of CD300A in immune homeostasis, inflammation regulation, and allergic response inhibition underscores its relevance in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Through the use of the KO Validated AES Rabbit Polyclonal Antibody, researchers can deepen their understanding of CD300A's function and pave the way for innovative treatments that manipulate immune function in disease settings.
Product Name:
[KO Validated] AES Rabbit Polyclonal Antibody
SKU:
CAB19944
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human AES (NP_945320.1).
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
166
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and AES knockout (KO) HeLa cells, using [KO Validated] AES Rabbit pAb (CAB19944) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
