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Anti-PGM1 Antibody (CAB19904)[KO Validated]

SKU:
CAB19904
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-PGM1 Antibody [KO Validated]
Antibody SKU:CAB19904
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human PGM1.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:10 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:293T
Immunogen:Recombinant protein of human PGM1.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5236
Uniprot:P36871
Cellular Location:Cytoplasm
Calculated MW:40kDa/61kDa/63kDa
Observed MW:61KDa
Anti-PGM1 Antibody [KO Validated] (CAB19904)Western blot analysis of extracts from normal (control) and PGM1 knockout (KO) 293T cells, using PGM1 antibody (CAB19904) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Synonyms:PGM1, CDG1T, GSD14
Background:The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
UniProt Protein Function:This enzyme participates in both the breakdown and synthesis of glucose.
NCBI Summary:The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010]
UniProt Code:P36871
NCBI GenInfo Identifier:585670
NCBI Gene ID:5236
NCBI Accession:P36871.3
UniProt Secondary Accession:P36871,Q16105, Q16106, Q5BKZ9, Q6NW22, Q86U74, Q96J40 Q9NTY4, B2R5N9, B4DPV0,
UniProt Related Accession:P36871
Molecular Weight:40,283 Da
NCBI Full Name:Phosphoglucomutase-1
NCBI Synonym Full Names:phosphoglucomutase 1
NCBI Official Symbol:PGM1  
NCBI Official Synonym Symbols:CDG1T; GSD14  
NCBI Protein Information:phosphoglucomutase-1
UniProt Protein Name:Phosphoglucomutase-1
UniProt Synonym Protein Names:Glucose phosphomutase 1
Protein Family:Phosphoglucomutase
UniProt Gene Name:PGM1  
UniProt Entry Name:PGM1_HUMAN

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