The KO Validated Rho Rabbit Monoclonal Antibody (CAB19106) is a cutting-edge research tool designed for the study of Rho proteins, key regulators of cytoskeletal dynamics and cell migration. This antibody, generated in rabbits, is highly specific to Rho proteins and has been validated for use in a variety of research applications, including immunofluorescence and flow cytometry.Rho proteins are essential for a wide range of cellular processes, including cell motility, adhesion, and division. Dysregulation of Rho signaling has been implicated in various diseases, including cancer and neurological disorders.
The KO Validated Rho Rabbit Monoclonal Antibody enables researchers to study the role of Rho proteins in these diseases and to identify potential therapeutic targets.Whether investigating the molecular mechanisms underlying cancer metastasis or exploring the role of Rho proteins in neuronal development, this antibody provides a reliable tool for precise and accurate detection of Rho proteins in a variety of biological samples. Researchers in the fields of cell biology, cancer research, and neuroscience will find this antibody indispensable for their studies.
Product Name:
[KO Validated] RhoA Rabbit Monoclonal Antibody
SKU:
CAB19106
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RhoA (P61586).
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Purification Method:
Affinity purification
Gene ID:
387
Clone Number:
ARC0372
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HUVEC cells, using RhoA antibody (CAB19106) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
