The LACTB Polyclonal Antibody (CAB7144) is a valuable tool for researchers studying LACTB, a protein involved in various cellular processes, including lipid metabolism and mitochondrial function. This rabbit polyclonal antibody specifically targets the LACTB protein and has been validated for use in Western blot applications.LACTB, also known as lactamase beta, is a key player in mitochondrial quality control and biogenesis, making it a promising target for investigation in metabolic disorders, cancer, and neurodegenerative diseases.
By detecting and analyzing LACTB expression in different cell types, researchers can gain valuable insights into the role of this protein in health and disease.With its high reactivity with human samples, the LACTB Polyclonal Antibody is a reliable tool for immunology and cancer research, offering opportunities for further understanding the molecular mechanisms underlying these conditions.
Product Name:
LACTB Rabbit Polyclonal Antibody
SKU:
CAB7144
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-290 of human LACTB (NP_116246.2).
This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
114294
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LACTB Rabbit pAb (CAB7144) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
