The MAPK13 Antibody (CAB16961) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.MAPK13, also known as p38delta, is involved in signaling pathways that regulate inflammation, stress response, and cell survival. Dysregulation of MAPK13 has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MAPK13 Antibody
SKU:
CAB16961
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SAPK4, PRKM13, MAPK 13, MAPK-13, p38delta, MAPK13
Positive Sample:
22Rv1, 5637, Mouse kidney, Mouse lung, Mouse pancreas, Rat kidney
Cellular Localization:
Cytoplasm, Cytosol, Nucleus.
Calculated MW:
42kDa
Observed MW:
42kDa
This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.
Purification Method
Affinity purification
Gene ID
5603
RRID
AB_2770279
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MAPK13 Rabbit pAb (CAB16961) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
