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FITC Anti-Mouse CD11a Antibody [FD441.8] (AGEL0154)

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SKU AGEL0154
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2b
Clone FD441.8
Conjugation FITC
Applications FC
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Description

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FITC Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody (FITC Conjugated) FD441-8 (AGEL0154) is a specialized antibody designed for researchers working with mouse samples to study CD11a, a cell surface glycoprotein known to be involved in immune responses and cell adhesion processes. This monoclonal antibody, conjugated with FITC for fluorescent detection, specifically targets CD11a, enabling precise identification and analysis in various experimental settings.CD11a, also referred to as integrin alpha L, plays a crucial role in mediating cellular interactions within the immune system, particularly in processes such as leukocyte adhesion and migration. By targeting CD11a, researchers can gain insights into immune cell behavior, inflammatory responses, and immune cell trafficking, contributing to advancements in immunology and related fields of study.

This FITC-conjugated monoclonal antibody FD441-8 (AGEL0154) offers high specificity and sensitivity in detecting CD11a in mouse samples, making it an invaluable tool for investigating immune system dynamics, inflammatory processes, and immune-mediated diseases. Whether utilized in flow cytometry, immunofluorescence, or other immunological techniques, this antibody facilitates the accurate visualization and quantification of CD11a-expressing cells, thereby enhancing research outcomes and deepening our understanding of immune system functionality and dysregulation.

Product Title:FITC Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0154
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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