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PerCP/Cyanine5.5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1202)

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SKU AGEL1202
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone R17 217.1.3/TIB-219
Conjugation PerCP/Cy5.5
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Description

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PerCP/Cyanine5.5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (R17-217.1.3, TIB-219) is a powerful tool for researchers working with CD71, a cell surface protein involved in iron metabolism and cell proliferation. This antibody, specifically designed for use in flow cytometry, enables the detection and quantification of CD71 expression in mouse samples with high specificity and sensitivity.CD71, also known as transferrin receptor 1, plays a vital role in cellular iron uptake and utilization, making it a key player in processes like erythropoiesis and cell growth. Understanding the expression levels and localization of CD71 is essential for studying conditions such as anemia, cancer, and developmental disorders where iron metabolism and cell proliferation are dysregulated.

By targeting CD71 with this monoclonal antibody, researchers can investigate the role of this protein in various biological processes, including cell cycle regulation, proliferation, and differentiation. With its PerCP-Cyanine5.5 conjugation, this antibody offers efficient detection and analysis capabilities, making it a valuable tool for studies in cell biology, oncology, and hematology.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1202
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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