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PE Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL0307)

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SKU AGEL0307
Product Type Antibody
Antibody Type Monoclonal Antibody
Host Species Rat
Isotype IgG2b
Clone M1/70
Conjugation PE
Applications FC
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Description

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PE Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (PE Conjugated, M1/70) is a valuable tool for researchers studying immune cell populations expressing the CD11b antigen. This antibody is specifically designed for flow cytometry applications, enabling the precise identification and analysis of CD11b-expressing cells in both mice and humans.CD11b, also known as integrin alpha M, is a cell surface receptor involved in cell adhesion and migration, particularly in the context of immune responses and inflammation. Its expression on various immune cells, including monocytes, macrophages, and granulocytes, makes it a key marker for studying the function and behavior of these cell populations in both health and disease.By utilizing the Mouse/Human CD11b Monoclonal Antibody (PE Conjugated, M1/70), researchers can gain insight into the distribution and activation status of CD11b-expressing cells in experimental models or clinical samples.

This antibody's high specificity and sensitivity ensure reliable and reproducible results, making it an essential reagent for studies focused on immune cell biology, inflammatory disorders, and immunotherapy research.Overall, the Mouse/Human CD11b Monoclonal Antibody (PE Conjugated, M1/70) offers a valuable tool for investigating the role of CD11b-positive immune cell populations, providing researchers with a deeper understanding of immune cell dynamics and potential therapeutic targets.

Product Title:PE Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL0307
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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