The MYPN Antibody (CAB16584) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. MYPN is a crucial component of the sarcomere, the basic unit of muscle contraction, and is involved in maintaining the structure and function of muscle cells. Dysregulation of MYPN has been implicated in various muscle disorders, making it a promising target for research in the fields of muscle biology and neuromuscular diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
MYPN Antibody
SKU:
CAB16584
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MYOP, RCM4, CMH22, NEM11, CMD1DD, MYPN
Positive Sample:
HepG2
Cellular Localization:
Cytoplasm, Nucleus, Myofibril, Sarcomere.
Calculated MW:
145kDa
Observed MW:
145kDa
Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
84665
RRID
AB_2770506
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using MYPN Rabbit pAb (CAB16584) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
