Description
NKX6-3 Antibody (PACO02546)
The NKX6-3 Polyclonal Antibody (PACO02546) is a valuable tool for researchers studying NKX6-3, a transcription factor essential for the development of pancreatic islet cells. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an excellent choice for Western blot applications. By binding to the NKX6-3 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in developmental biology and diabetes research.
NKX6-3 plays a crucial role in pancreatic development and function, making it a key target for investigating diseases such as diabetes mellitus. Understanding the function and regulation of NKX6-3 is essential for elucidating the mechanisms underlying pancreatic development and dysfunction. The NKX6-3 Polyclonal Antibody is a valuable tool for researchers aiming to advance our knowledge of pancreatic biology and develop new therapeutic interventions for pancreatic disorders.
| Antibody Name: | NKX6-3 Antibody |
| Antibody SKU: | PACO02546 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Monkey |
| Immunogen: | synthesized peptide derived from the Internal region of human Nkx-6.3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NKX6-3; Homeobox protein Nkx-6.3 |
| UniProt Protein Function: | NKX6-3: Putative transcription factor, which may be involved in patterning of central nervous system and pancreas. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 8p11.21 |
| NCBI Summary: | The NKX family of homeodomain proteins controls numerous developmental processes. Members of the NKX6 subfamily, including NKX6-3, are involved in development of the central nervous system (CNS), gastrointestinal tract, and pancreas (Alanentalo et al., 2006 [PubMed 16326147]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | A6NJ46 |
| NCBI GenInfo Identifier: | 160417300 |
| NCBI Gene ID: | 157848 |
| NCBI Accession: | A6NJ46.1 |
| UniProt Secondary Accession: | A6NJ46,Q96LR0, |
| UniProt Related Accession: | A6NJ46 |
| Molecular Weight: | 14,322 Da |
| NCBI Full Name: | Homeobox protein Nkx-6.3 |
| NCBI Synonym Full Names: | NK6 homeobox 3 |
| NCBI Official Symbol: | NKX6-3Â Â |
| NCBI Official Synonym Symbols: | NKX6.3Â Â |
| NCBI Protein Information: | homeobox protein Nkx-6.3 |
| UniProt Protein Name: | Homeobox protein Nkx-6.3 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | NKX6-3Â Â |
| UniProt Entry Name: | NKX63_HUMAN |
