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Key Features

PE/Cyanine5 Anti-Human CD62L Antibody [HI62L] (AGEL3487)

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SKU AGEL3487
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, k
Clone HI62L
Conjugation PE/Cyanine5
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Description

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PE/Cyanine5 Anti-Human CD62L Antibody [HI62L]

The PE Cyanine5 Anti-Human CD62L Antibody (HI62L) offered by Assay Genie is a cutting-edge tool for researchers studying immune cell adhesion and migration processes. This antibody, optimized for use in flow cytometry, specifically targets CD62L, a key adhesion molecule involved in lymphocyte trafficking and homing.CD62L, also known as L-selectin, plays a critical role in immune cell surveillance and activation by facilitating the binding of lymphocytes to high endothelial venules in secondary lymphoid organs. Its expression pattern and function make it a vital marker for characterizing subsets of T cells, B cells, and other leukocytes.The PE Cyanine5 conjugate provides superior sensitivity and signal-to-noise ratio, allowing for precise identification and quantification of CD62L-expressing cells in complex samples.

This antibody is validated for use in a variety of research applications, including immunophenotyping, cell sorting, and functional assays aimed at elucidating the role of CD62L in immune responses.By utilizing the PE Cyanine5 Anti-Human CD62L Antibody (HI62L), researchers can delve deeper into the mechanisms governing immune cell migration and activation, paving the way for new insights into immune-related disorders such as inflammation, infection, and autoimmune diseases. Stay at the forefront of immunology research with this advanced antibody from Assay Genie.

Product Title:PE/Cyanine5 Anti-Human CD62L Antibody [HI62L]
SKU:AGEL3487
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI62L
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine5 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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