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PE/Cyanine7 Anti-Human CD14 Antibody [M5E2] (AGEL2385)

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SKU AGEL2385
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, κ
Clone M5E2
Conjugation PE/Cyanine7
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Description

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PE/Cyanine7 Anti-Human CD14 Antibody [M5E2]

The PE-Cyanine7 Anti-Human CD14 Antibody (M5E2) from Assay Genie is a valuable tool for researchers studying CD14, a key cell surface marker involved in innate immunity and inflammation. This antibody, optimized for use in flow cytometry applications, specifically targets human CD14 and allows for precise detection and analysis in various cell populations.CD14 is a pivotal receptor expressed on monocytes and macrophages, playing a critical role in the recognition of bacterial lipopolysaccharides and initiation of inflammatory responses. By targeting CD14, researchers can gain insights into immune responses, inflammatory pathways, and diseases such as sepsis and atherosclerosis.

The PE-Cyanine7 Anti-Human CD14 Antibody (M5E2) offers high sensitivity and specificity, enabling accurate quantification and characterization of CD14-expressing cells. With its superior performance and reliability, this antibody is a valuable asset for studies in immunology, infectious diseases, and inflammatory disorders. Trust Assay Genie's expertise in antibody development to advance your research in CD14 biology and related areas.

Product Title:PE/Cyanine7 Anti-Human CD14 Antibody [M5E2]
SKU:AGEL2385
Size:20 Tests, 100 Tests, 200 Tests
Clone No:M5E2
Synonyms:Monocyte differentiation antigen CD14;CD14;Myeloid cell-specific leucine-rich glycoprotein;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine7 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08571
Gene ID:929
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

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