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PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL3238)

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SKU AGEL3238
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG1, k
Clone M/K-2.7
Conjugation PE/AF594
€63 - €144
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Description

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PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7]

The PE GenieFluor 594 Anti-Mouse CD106 Antibody (M/K-2.7) is a powerful tool for researchers studying CD106, a cell surface glycoprotein involved in immune responses and inflammation modulation. This antibody, specifically designed for use with mouse samples, is produced to exacting standards for reliable results in flow cytometry and immunofluorescence applications.CD106, also known as vascular cell adhesion molecule 1 (VCAM-1), plays a crucial role in mediating leukocyte adhesion and transmigration during inflammatory responses. Its expression is tightly regulated and serves as a key marker for endothelial cell activation, making it a vital target for investigations into conditions such as atherosclerosis, inflammatory diseases, and autoimmune disorders.

By utilizing the PE GenieFluor 594 Anti-Mouse CD106 Antibody, researchers can accurately detect and quantify CD106 expression on endothelial cells and other relevant cell types, shedding light on the mechanisms underlying immune cell recruitment and vascular inflammation. This antibody provides a valuable tool for gaining insights into the pathophysiology of various diseases and identifying potential therapeutic targets for intervention.

Product Title:PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL3238
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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