Description
Phospho-FAM129A (Ser602) Antibody (PACO23915)
The Phospho-FAM129A (Ser602) Antibody (PAC023915) is a valuable tool for researchers studying FAM129A, a protein involved in cell signaling pathways and regulation. This antibody, produced using high-quality materials and methods, is specifically designed to detect phosphorylation of FAM129A at the Ser602 site, allowing for precise analysis in Western blot applications.FAM129A, also known as Niban, has been implicated in various cellular processes, including cell growth, apoptosis, and metabolic regulation. Phosphorylation of FAM129A at Ser602 is known to play a role in modulating its activity and function, making this antibody particularly useful for investigating the dynamics of FAM129A signaling in different cell types and contexts.
Research on FAM129A and its phosphorylation status is crucial for understanding its role in cancer development, neurodegenerative diseases, and metabolic disorders. By using the Phospho-FAM129A (Ser602) Antibody, researchers can delve deeper into the mechanisms underlying FAM129A function and potentially uncover new therapeutic targets for these conditions.
| Antibody Name: | Phospho-FAM129A (Ser602) Antibody (PACO23915) |
| Antibody SKU: | PACO23915 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence around phosphorylation site of serine 602 (R-A-S(p)-A-I) derived from Human Niban. |
| Form: | Liquid |
| Storage Buffer: | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis in vitro kinase assays were performed by mixing purified bacterially expressed WT His-Niban or the His-Niban S602A with or without purified active AKT1 using Niban (Phospho-Ser602) Antibody. |
| Background: | Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response |
| Synonyms: | FAM129A |
| UniProt Protein Function: | FAM129A: Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response. Belongs to the Niban family. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 1q25 Cellular Component: membrane; cytoplasm; plasma membrane Molecular Function:protein binding Biological Process: negative regulation of protein amino acid phosphorylation; positive regulation of translation; positive regulation of protein amino acid phosphorylation |
| UniProt Code: | Q9BZQ8 |
| NCBI GenInfo Identifier: | 22256936 |
| NCBI Gene ID: | 116496 |
| NCBI Accession: | Q9BZQ8.1 |
| UniProt Secondary Accession: | Q9BZQ8,Q2TTR2, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9 |
| UniProt Related Accession: | Q9BZQ8 |
| Molecular Weight: | 928 |
| NCBI Full Name: | Protein Niban |
| NCBI Synonym Full Names: | family with sequence similarity 129, member A |
| NCBI Official Symbol: | FAM129AÂ Â |
| NCBI Official Synonym Symbols: | GIG39; NIBAN; C1orf24Â Â |
| NCBI Protein Information: | protein Niban; cell growth-inhibiting gene 39 protein |
| UniProt Protein Name: | Protein Niban |
| UniProt Synonym Protein Names: | Cell growth-inhibiting gene 39 protein; Protein FAM129A |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM129AÂ Â |
| UniProt Entry Name: | NIBAN_HUMAN |
| Antibodies |
| FAM129A Antibody (PACO09207) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
