The Phospho-GJA1 (S368) Polyclonal Antibody (CABP0876) offered by Assay Genie is a high-quality antibody designed for research involving the phosphorylation of GJA1 at serine 368. GJA1, also known as Connexin 43, is a critical protein involved in cell-to-cell communication and signaling in various cellular processes.This antibody, raised in rabbits, is highly specific and reacts strongly with human samples, making it an excellent tool for Western blot applications. It specifically recognizes the phosphorylated form of GJA1 at serine 368, allowing for precise detection and analysis in a variety of cell types.Phosphorylation of GJA1 at serine 368 has been implicated in a range of cellular functions, including cell growth, differentiation, and intracellular signaling pathways.
Understanding the role of this phosphorylation event is crucial for research in areas such as cell biology, cancer biology, and developmental biology.Overall, the Phospho-GJA1 (S368) Polyclonal Antibody (CABP0876) is a valuable tool for researchers looking to study the phosphorylation status of GJA1 and its impact on cellular processes. Its specificity and sensitivity make it an ideal choice for studies aiming to elucidate the functional significance of this post-translational modification in various biological contexts.
Product Name:
Phospho-GJA1-S368 Rabbit Polyclonal Antibody
SKU:
CABP0876
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around S368 of human GJA1 (NP_000156.1).
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
Purification Method:
Affinity purification
Gene ID:
2697
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Rat heart using Phospho-Connexin 43-S368 Rabbit pAb (CABP0876) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
