The Phospho-MAP2K6 (S207) Polyclonal Antibody (CABP0393) is a valuable tool for researchers studying MAP2K6, a key regulator of cell signaling pathways involved in cell growth, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific to the phosphorylated form of MAP2K6 at Serine 207 and is validated for use in Western blot applications.MAP2K6, also known as dual specificity mitogen-activated protein kinase kinase 6, plays a crucial role in mediating cellular responses to various extracellular stimuli, including growth factors, cytokines, and stress signals.
Phosphorylation of MAP2K6 at Serine 207 has been linked to activation of downstream signaling cascades that regulate processes such as cell proliferation and survival.Research into the function of MAP2K6 and its phosphorylation status is important for understanding its role in diseases such as cancer, neurodegenerative disorders, and inflammatory conditions. By studying the activity of MAP2K6 at the molecular level, researchers can gain insights into potential therapeutic targets for these diseases and develop strategies for modulating cell signaling pathways for therapeutic benefit.
Product Name:
Phospho-MEK6-S207 Rabbit Polyclonal Antibody
SKU:
CABP0393
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A phospho specific peptide corresponding to residues surrounding S207 of human MAP2K6
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Purification Method:
Affinity purification
Gene ID:
5608
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HL60 cells, using Phospho-MEK6-S207 Rabbit pAb (CABP0393).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
