The PPP6R2 Antibody (CAB8359) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PPP6R2 protein, this antibody enables accurate detection and analysis in different cell types, making it an excellent choice for investigations in the fields of cell biology and signal transduction.PPP6R2 is a critical component in the regulation of protein dephosphorylation, playing a vital role in controlling cellular processes such as cell cycle progression and DNA damage response.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
PPP6R2 Antibody
SKU:
CAB8359
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PP6R2, SAPS2, SAP190, KIAA0685, PPP6R2
Positive Sample:
HepG2, 293T, Jurkat
Cellular Localization:
Cytoplasm.
Calculated MW:
105kDa
Observed MW:
105kDa
The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment.
Purification Method
Affinity purification
Gene ID
9701
RRID
AB_2771795
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PPP6R2 Rabbit pAb (CAB8359) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 10s.
