The PRMT8 Polyclonal Antibody is a valuable tool for researchers studying PRMT8, a protein involved in various cellular processes including gene regulation and cell signaling. This antibody, produced in rabbits, shows high specificity and sensitivity for PRMT8 in human samples, making it suitable for use in Western blot applications. By binding to PRMT8, this antibody allows for the detection and analysis of PRMT8 levels in different cell types, making it ideal for studies in neurobiology and cancer research.PRMT8, a member of the protein arginine methyltransferase (PRMT) family, plays a crucial role in modulating gene expression through the post-translational modification of proteins.
Its dysregulation has been implicated in various diseases, including neurological disorders and cancer. By studying the function of PRMT8, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment strategies. Overall, the PRMT8 Polyclonal Antibody is a reliable tool for researchers looking to investigate the role of PRMT8 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset in advancing our understanding of PRMT8 function and exploring its potential as a therapeutic target.
Product Name:
PRMT8 Polyclonal Antibody
SKU:
CAB2326
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3).
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).
Purification Method:
Affinity purification
Gene ID:
56341
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRMT8 Rabbit pAb (CAB2326).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
