The PROCR Antibody (CAB13641) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody is produced in rabbits and is highly specific to human ProC Reactive Protein, making it ideal for Western blot applications.ProC Reactive Protein is an important biomarker in the diagnosis and monitoring of inflammatory diseases, cardiovascular disorders, and sepsis. By detecting the presence and levels of ProC Reactive Protein in samples, researchers can gain insights into the immune response and overall health status of individuals.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PROCR Antibody
SKU:
CAB13641
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CCCA, EPCR, CCD41, PROCR
Positive Sample:
U-87MG
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
27kDa
Observed MW:
45kDa
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
Purification Method
Affinity purification
Gene ID
10544
RRID
AB_2760503
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from U-87MG cells, using PROCR Rabbit pAb (CAB13641) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Immunohistochemistry analysis of paraffin-embedded Rat liver using PROCR Rabbit pAb (CAB13641) at dilution of 1:200 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
