The PROP1 Antibody (CAB16963) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific to human samples and is suitable for use in Western blot applications. By binding to the PROP1 protein, researchers can effectively detect and analyze its expression in various cell types, making this antibody ideal for studies in endocrinology and developmental biology.The PROP1 protein is a critical regulator of pituitary gland development and hormone production, making it a key player in the endocrine system.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
PROP1 Antibody
SKU:
CAB16963
Size:
20μL, 100μL
Reactivity:
Mouse
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CPHD2, PROP-1, PROP1
Positive Sample:
Mouse brain
Cellular Localization:
Nucleus.
Calculated MW:
25kDa
Observed MW:
25kDa
This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.
Purification Method
Affinity purification
Gene ID
5626
RRID
AB_2771841
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using PROP1 Rabbit pAb (CAB16963) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 50s.
