The PGE receptor EP2 (PTGER3) Antibody (CAB4057) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is generated in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications for the detection and analysis of PTGER3 protein levels.PTGER3, also known as EP3, is known to play a crucial role in mediating the effects of prostaglandin E2 (PGE2) on cells, influencing signal transduction pathways that regulate cell proliferation, differentiation, and apoptosis. Dysregulation of PTGER3 signaling has been implicated in various diseases, including inflammation-related disorders, cancer, and gastrointestinal diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
PGE receptor EP2 (PTGER3) Antibody
SKU:
CAB4057
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
5733
RRID
AB_2765475
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGE receptor EP3 (PTGER3) Rabbit pAb (CAB4057) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
