The PTPN20A Polyclonal Antibody (PACO20292) is specifically designed for research involving PTPN20A, a protein tyrosine phosphatase involved in regulating cellular signaling pathways. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the PTPN20A protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent tool for studies in cell signaling, cancer research, and potentially other therapeutic applications.
PTPN20A, also known as non-receptor type protein tyrosine phosphatase, plays a crucial role in mediating cellular processes such as cell growth, differentiation, and apoptosis. Its involvement in cellular signaling makes it a promising target for research into diseases like cancer, neurological disorders, and diabetes. Understanding the function of PTPN20A is essential for developing targeted therapies that can regulate cellular signaling pathways and potentially treat various diseases at the molecular level.
Antibody Name:
PTPN20A Antibody (PACO20292)
Antibody SKU:
PACO20292
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human PTPN20A/PTPN20B
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20292(PTPN20A/PTPN20B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20292(PTPN20A/PTPN20B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants.
Synonyms:
protein tyrosine phosphatase, non-receptor type 20B
UniProt Protein Function:
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.
