The PYCR1 Antibody (CAB6959) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high specificity and sensitivity for detecting PYCR1 in human samples, making it suitable for Western blot applications. By binding to the PYCR1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies related to metabolism, cancer, and cell growth.PYCR1 is a key enzyme in the proline biosynthesis pathway, playing a crucial role in various cellular processes such as collagen production, oxidative stress response, and cell proliferation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PYCR1 Antibody
SKU:
CAB6959
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
5831
RRID
AB_2767517
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PYCR1 Rabbit pAb (CAB6959) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
