The RAB18 Antibody (CAB2812) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in immunofluorescence and immunohistochemistry applications.Rab18 is a small GTPase protein that is involved in various cellular processes, including Golgi apparatus organization, lipid droplet formation, and autophagy. Dysregulation of Rab18 has been implicated in diseases such as obesity, diabetes, and neurodegenerative disorders, making it a promising target for therapeutic intervention.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
RAB18 Antibody
SKU:
CAB2812
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
WARBM3, RAB18LI1, RAB18
Positive Sample:
SH-SY5Y, A375, 293T, MCF7, Mouse liver, Mouse kidney, Rat liver
Cellular Localization:
Cell Membrane, Cytoplasmic Side, Lipid-Anchor.
Calculated MW:
23kDa
Observed MW:
23kDa
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.
Purification Method
Affinity purification
Gene ID
22931
RRID
AB_2764650
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RAB18 Rabbit pAb (CAB2812) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
