null

Human ALK/ACVRL1 Recombinant Protein (RPES4895)

SKU:
RPES4895
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cardiovascular
€117
Frequently bought together:

Description

system_update_altDatasheet

Human ALK/ACVRL1 Recombinant Protein

Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.