The Apolipoprotein A1 (APOA1) protein is a secreted member of the Apolipoprotein A1/A4/E family. The major protein component of high-density lipoprotein (HDL) in plasma is APOA1. ApoA1 is a protein that has been linked to several physiological functions, such as cholesterol synthesis and metabolism; lipid synthesis and transport; and steroid synthesis. APOA1 promotes cholesterol efflux from tissues to the liver. Mutations in this gene cause HDL deficiencies, such as Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. ApoA-I is involved in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin. Apolipoprotein A-I/ApoAI Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Apolipoprotein A-I/ApoAI Recombinant Protein (RPES2825)
Recombinant Human Apolipoprotein A-I is produced by our E.coli expression system and the target gene encoding Arg19-Gln267 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
29.0 kDa
AP Mol Mass:
27-29 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
