Description
| SKU: | RPCB2212 |
| Size: | 10 μg, 20 μg, 50 μg, 100 μg |
| Tag: | C-8xHis |
| Reactivity: | Human |
| Protein Description: | RAMP3 belongs to the RAMP family. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1) .Required for the transport of CALCRL and GPER1 receptors to the plasma membrane .Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner.Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 .Together with CALCR, act as a receptor complex for amylin/IAPP. |
| Endotoxin: | < 0.1 EU/μg of the protein by LAL method. |
| Purity: | ≥ 95 % as determined by SDS-PAGE. |
| Formulation: | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Gene ID: | 10268 |
| Storage: | Store at -70°C. This product is stable at ≤ -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Swiss-Prot: | NP_005847.1 |
 | Recombinant Human RAMP3(M33L) Protein was determined by SDS- PAGE with Coomassie Blue. Measured by its binding ability in a functional ELISA. |
 | Immobilized Human RAMP3(M33L) (Catalog: RP0782LQ) at 2 μg/mL (100 μL/well) can bind RAMP3 Rabbit pAb with a linear range of 0. 10-8.48 ng/mL. |
