The REG3A Polyclonal Antibody (CAB12479) is a valuable tool for researchers studying REG3A, a secretory protein involved in various biological processes, including intestinal homeostasis and host defense. This antibody, produced in rabbits, is highly specific for human samples and is ideal for applications such as Western blotting.REG3A, also known as regenerating islet-derived protein 3-alpha, plays a crucial role in maintaining the integrity of the intestinal barrier and protecting against microbial infections.
Its dysregulation has been linked to inflammatory bowel diseases and other gastrointestinal disorders, making it a promising target for therapeutic interventions.By using the REG3A Polyclonal Antibody, researchers can accurately detect and analyze REG3A protein expression in different cell types and tissues, providing valuable insights into its function and potential involvement in disease pathology. This antibody is a valuable tool for research in the fields of gastroenterology, immunology, and microbiology.
Product Name:
REG3A Rabbit Polyclonal Antibody
SKU:
CAB12479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-175 of human REG3A (NP_002571.1).
This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
5068
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using REG3A Rabbit pAb (CAB12479) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
