The RMI2 Antibody (CAB8523) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the RMI2 protein, this antibody allows for the detection and analysis of RMI2 in various cell types, making it ideal for studies in molecular biology and cancer research.RMI2, also known as RecQ-mediated genome instability protein 2, is essential for stabilizing DNA structures and promoting genomic integrity. Dysregulation of RMI2 has been linked to mutations and chromosomal abnormalities associated with cancer and other genetic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
RMI2 Antibody
SKU:
CAB8523
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BLAP18, C16orf75, RMI2
Positive Sample:
HeLa, MCF7
Cellular Localization:
Nucleus.
Calculated MW:
16kDa
Observed MW:
16kDa
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).
Purification Method
Affinity purification
Gene ID
116028
RRID
AB_2772026
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RMI2 Rabbit pAb (CAB8523) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
