The S100 Rabbit Monoclonal Antibody (CAB19107) is a powerful tool for researchers studying the S100 protein family, which plays a key role in various cellular processes such as cell cycle progression, cell differentiation, and cell migration. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it ideal for use in a variety of research applications, including immunofluorescence, immunohistochemistry, and flow cytometry.The S100 protein family is known for its involvement in cancer progression, inflammation, and neurodegenerative diseases. By targeting S100 proteins with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially identify novel therapeutic targets.
Additionally, the S100 Rabbit Monoclonal Antibody (CAB19107) may also be useful in diagnostic applications for detecting abnormal expression levels of S100 proteins in patient samples.Overall, this antibody provides researchers with a reliable tool for investigating the functional role of S100 proteins in various biological processes and diseases, ultimately advancing our understanding of these critical signaling molecules.
Product Name:
S100/S100A1 Rabbit Monoclonal Antibody
SKU:
CAB19107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-94 of human S100/S100A1 (P23297).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Purification Method:
Affinity purification
Gene ID:
6271
Clone Number:
ARC0404
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using S100/S100A1 antibody (CAB19107) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
