The S100PBP Antibody (PAC038114) is a valuable tool for researchers studying S100PBP, a member of the S100 family of calcium-binding proteins. This polyclonal antibody is raised in rabbits and exhibits high reactivity with human samples, making it a reliable choice for Western blot applications. By specifically targeting the S100PBP protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in areas such as immunology and cancer research.S100PBP is known to be involved in various cellular processes, including cell growth, differentiation, and apoptosis. Its dysregulation has been implicated in multiple diseases, making it a promising target for further investigation.
By utilizing this antibody, researchers can gain valuable insights into the function and activity of S100PBP, potentially leading to the development of novel therapeutic strategies for conditions such as cancer and inflammatory disorders.Overall, the S100PBP Antibody (PAC038114) offers a reliable and specific tool for researchers seeking to explore the role of S100PBP in health and disease. Its high reactivity and validation for Western blot applications make it a valuable asset for advancing our understanding of this important protein.
Antibody Name:
S100PBP Antibody (PACO38114)
Antibody SKU:
PACO38114
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human S100P-binding protein (276-408AA)
Immunohistochemistry of paraffin-embedded human lung cancer using PACO38114 at dilution of 1:100.
Background:
nucleus, calcium-dependent protein binding
Synonyms:
S100P-binding protein (S100P-binding protein Riken), S100PBP, S100PBPR
UniProt Protein Function:
Subunit structure: Interacts with S100P. Ref.5Subcellular location: Nucleus. Note: Colocalizes with S100P in the nucleus. Ref.5Tissue specificity: Expressed in brain, spleen, and lung. Not detected in pancreas or liver. In pancreas, expressed predominantly in islet cells and to a lesser extent in acinar cells, but not expressed in ductal cells. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Detected in pancreatic ductal adenocarcinoma cells (at protein level). Not detected in non-neoplastic ductal epithelium (at protein level). Ref.5 Ref.6Sequence caution: The sequence BAB14335.1 differs from that shown. Reason: Erroneous initiation.
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that was originally identified by its interaction with S100 calcium-binding protein P. Expression of this protein has been reported to be associated with pancreatic ductal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
