The SBF1 Antibody (CAB12354) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit immunization, is highly specific for human samples and is validated for use in Western blot applications. It targets the SBF1 protein, allowing for accurate detection and analysis in various cellular contexts, making it ideal for studies in cell biology and cancer research.SBF1 is a critical player in the control of cell cycle progression and proliferation, making it a promising target for understanding the mechanisms underlying diseases like cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
SBF1 Antibody
SKU:
CAB12354
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MTMR5, CMT4B3, DENND7A, SBF1
Positive Sample:
Raji, Jurkat, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
208kDa
Observed MW:
208kDa
This gene encodes a member of the protein-tyrosine phosphatase family. However, the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot-Marie-Tooth disease 4B3. Pseudogenes of this gene have been defined on chromosomes 1 and 8.
Purification Method
Affinity purification
Gene ID
6305
RRID
AB_2759196
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SBF1 Rabbit pAb (CAB12354) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
