SDCCAG3 Antibody (PACO14324)
- SKU:
- PACO14324
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SDCCAG3 Antibody (PACO14324) |
| Antibody SKU: | PACO14324 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human SDCCAG3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14324(SDCCAG3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Primary antibody: PACO14324(SDCCAG3 Antibody) at dilution 1/500 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14324(SDCCAG3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | SDCCAG3 protein contains the region similar to the coiled-coil domain of the myosin tail. The same domain is present in the proteins related to the organelles/proteins trafficking, such as kinesin, Golgin-160, and dynein. SDCCAG3 function might be related to protein trafficking and secretion, May be involved in modulation of TNF response, May be involved in presentation of TNFRSF1A on the cell surface. Interaction of SDCCAG3 with the Arf GTPase activating protein GIT1 (G protein-coupled receptor kinase interactor-1). Overexpression of an ArfGAP-negative version of GIT1 also results in an increased number of multinucleate cells suggesting regulation of Arf-mediated vesicular trafficking or signaling via SDCCAG3. |
| Synonyms: | serologically defined colon cancer antigen 3 |
| UniProt Protein Function: | SDCCAG3: May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface. Belongs to the SDCCAG3 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: recycling endosome; retromer complex; early endosome; midbody; endosome Molecular Function:protein binding Biological Process: protein transport; cell division; cell cycle; regulation of cytokinesis |
| UniProt Code: | Q96C92 |
| NCBI GenInfo Identifier: | 172045853 |
| NCBI Gene ID: | 10807 |
| NCBI Accession: | Q96C92.3 |
| UniProt Secondary Accession: | Q96C92,O60525, Q5SXN1, Q5SXN2, Q5SXN3, Q5SXN4, Q5SXN8 Q6V704, Q9NVY5, A6NCP1, |
| UniProt Related Accession: | Q96C92 |
| Molecular Weight: | 412 |
| NCBI Full Name: | Serologically defined colon cancer antigen 3 |
| NCBI Synonym Full Names: | serologically defined colon cancer antigen 3 |
| NCBI Official Symbol: | SDCCAG3Â Â |
| NCBI Official Synonym Symbols: | NY-CO-3Â Â |
| NCBI Protein Information: | serologically defined colon cancer antigen 3; antigen NY-CO-3 |
| UniProt Protein Name: | Serologically defined colon cancer antigen 3 |
| UniProt Synonym Protein Names: | Antigen NY-CO-3 |
| UniProt Gene Name: | SDCCAG3Â Â |
| UniProt Entry Name: | SDCG3_HUMAN |
| Antibodies | ELISA Kits |
| SDCCAG3 Antibody (PACO12070) | Human SDCCAG3 (Serologically defined colon cancer antigen 3) ELISA Kit |
| Human Serologically defined colon cancer antigen 3 (SDCCAG3) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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