The SRGN Polyclonal Antibody (CAB13340) is a versatile tool for researchers studying the role of SRGN, a cell surface proteoglycan, in various biological processes. This antibody, produced in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.SRGN, also known as Serglycin, is involved in cell adhesion, migration, and inflammation, making it a key player in immune responses and cancer progression. By targeting SRGN with this polyclonal antibody, researchers can detect and analyze the protein in different cell types, providing valuable insights into its function.
Furthermore, understanding the role of SRGN is essential for developing targeted therapies for diseases such as cancer, inflammatory disorders, and autoimmune conditions. By using the SRGN Polyclonal Antibody, researchers can uncover new avenues for treatment and improve our understanding of the complex mechanisms underlying these diseases.
Product Name:
SRGN Rabbit Polyclonal Antibody
SKU:
CAB13340
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-158 of human SRGN (NP_002718.2).
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5552
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SRGN antibody (CAB13340) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
