The TESK1 Polyclonal Antibody (PACO05198) is a crucial tool for researchers studying TESK1, a protein kinase involved in cellular processes such as cell migration and cytoskeletal organization. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is specifically validated for use in Western blot applications.TESK1 is known to play a key role in cell signaling pathways that regulate actin dynamics, which are important for processes like cell motility and adhesion. By targeting the TESK1 protein, this antibody enables precise detection and analysis in various cell types, making it an invaluable resource for studies in cell biology and cancer research.
The role of TESK1 in cellular functions makes it a promising target for investigating diseases like cancer, where aberrant cell movement and cytoskeletal rearrangement occur. Understanding the mechanisms regulated by TESK1 can provide insights into potential therapeutic strategies for cancer treatment and other related conditions. Researchers utilizing the TESK1 Polyclonal Antibody can advance their understanding of TESK1 function and its implications in various biological processes.
Antibody Name:
TESK1 Antibody (PACO05198)
Antibody SKU:
PACO05198
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:40000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the Internal region of human TESK1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TESK1; Dual specificity testis-specific protein kinase 1; Testicular protein kinase 1
UniProt Protein Function:
TESK1: a TKL kinase of the LISK fanily. Its testicular germ cell-specific expression and developmental pattern of expression in the mouse suggests that this kinase plays an important role at and after the meiotic phase of spermatogenesis.Protein type: EC 2.7.12.1; Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); TKL group; LISK family; TESK subfamilyChromosomal Location of Human Ortholog: 9p13Cellular Component: cytosolMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
