The TET1 Monoclonal Antibody (CAB23162) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, produced using advanced technology, specifically targets the TET1 protein and is highly specific for human samples, providing reliable and accurate results in a variety of experimental settings.TET1 plays a crucial role in regulating gene expression by modifying DNA methylation patterns, making it a key player in processes such as embryonic development, stem cell differentiation, and tumorigenesis. The TET1 Monoclonal Antibody enables scientists to detect and study the expression levels and localization of TET1 in different cell types, offering valuable insights into its function and potential therapeutic applications.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
TET1 Monoclonal Antibody
SKU:
CAB23162
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC59030
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LCX, CXXC6, bA119F7.1, TET1
Positive Sample:
Hep G2, Mouse brain, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
235kDa
Observed MW:
310kDa
DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by this gene is a demethylase that belongs to the TET (ten-eleven translocation) family. Members of the TET protein family play a role in the DNA methylation process and gene activation.
Purification Method
Affinity purification
Gene ID
80312
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using TET1 Rabbit mAb (CAB23162) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
