The TET1 Polyclonal Antibody is a key tool for researchers studying TET1, a protein involved in DNA demethylation and gene regulation. Raised in rabbits, this antibody is highly specific and reliable for detecting TET1 in human samples, making it ideal for use in Western blot applications. By binding to TET1, this antibody enables researchers to study the role of this protein in epigenetic regulation and its implications in various cellular processes.TET1 is a member of the TET family of proteins which play a crucial role in DNA demethylation, a process that is essential for gene expression and cell differentiation.
Dysregulation of TET1 has been linked to various diseases, including cancer and neurological disorders, making it a promising target for therapeutic intervention. By using the TET1 Polyclonal Antibody, researchers can gain valuable insights into the function of TET1 and its impact on disease development, paving the way for novel treatment strategies.
Product Name:
TET1 Polyclonal Antibody
SKU:
CAB21766
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 820-978 of mouse TET1 (NP_081660.1).
Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
Purification Method:
Affinity purification
Gene ID:
52463
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using TET1 Rabbit pAb (CAB21766) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
