The TMEM119 Polyclonal Antibody is a valuable tool for research focused on TMEM119, a transmembrane protein predominantly expressed in microglia, a type of immune cell in the brain. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications such as Western blot and immunohistochemistry.TMEM119 is known for its role in the regulation of microglial function and neuroinflammation, making it a key target for studies in neuroscience and neurodegenerative diseases. By binding to the TMEM119 protein, this polyclonal antibody enables researchers to investigate the expression and localization of TMEM119 in different experimental settings, providing insights into its function in brain health and disease.
Given the importance of microglia in maintaining brain homeostasis and responding to injury or pathology, the TMEM119 Polyclonal Antibody offers researchers a valuable tool for studying the role of TMEM119 in neuroinflammation, neurodegeneration, and other neurological conditions. Its specific targeting of TMEM119 makes it a reliable reagent for advancing our understanding of microglial biology and potential therapeutic interventions targeting this cell population.
Product Name:
TMEM119 Polyclonal Antibody
SKU:
CAB22118
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-270 of human TMEM119 (NP_859075.2).
Involved in positive regulation of bone mineralization; positive regulation of osteoblast differentiation; and positive regulation of osteoblast proliferation. Located in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
338773
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TMEM119 Rabbit pAb (CAB22118) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
