The TSR1 Antibody (CAB4842) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in Western blot applications. It specifically binds to the TSR1 protein, enabling accurate detection and analysis in various cell types, making it an ideal tool for studies in molecular biology and cancer research.TSR1, also known as ribosome biogenesis protein TSR1 homolog, is essential for ribosome assembly and plays a crucial role in protein synthesis. Dysregulation of TSR1 has been linked to cancer development and progression, making it a promising target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
TSR1 Antibody
SKU:
CAB4842
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TSR1
Positive Sample:
HepG2, Mouse testis
Cellular Localization:
Nucleus, Nucleolus.
Calculated MW:
92kDa
Observed MW:
110kDa
Enables RNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of preribosome, small subunit precursor.
Purification Method
Affinity purification
Gene ID
55720
RRID
AB_2765899
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSR1 Rabbit pAb (CAB4842) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
