The ZFYVE1 Polyclonal Antibody (CAB7527) is a powerful tool for researchers studying the ZFYVE1 protein, an important player in cellular processes such as membrane trafficking and autophagy. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for a variety of applications including Western blot analysis.ZFYVE1, also known as zinc finger FYVE-type containing 1, is involved in the regulation of intracellular trafficking and plays a crucial role in maintaining cellular homeostasis.
Dysregulation of ZFYVE1 has been linked to various diseases, including cancer and neurological disorders, highlighting the significance of studying this protein in various research fields.By utilizing the ZFYVE1 Polyclonal Antibody (CAB7527), researchers can gain valuable insights into the function and regulation of ZFYVE1, ultimately contributing to our understanding of cellular processes and diseases associated with its dysfunction.
Product Name:
ZFYVE1 Rabbit Polyclonal Antibody
SKU:
CAB7527
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-735 of human ZFYVE1 (NP_067083.1).
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
53349
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using ZFYVE1 antibody (CAB7527) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
