The ZFYVE16 Polyclonal Antibody (CAB7766) is a valuable tool for researchers studying the ZFYVE16 protein, a key player in autophagy and intracellular trafficking pathways. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in techniques such as Western blotting.ZFYVE16, also known as Protrudin, is involved in the formation of autophagosomes, the organelles responsible for degrading and recycling cellular components. Dysregulation of autophagy has been implicated in various diseases, making ZFYVE16 an important target for research in cancer, neurodegenerative disorders, and metabolic conditions.
By utilizing the ZFYVE16 Polyclonal Antibody, researchers can detect and analyze the expression of ZFYVE16 in different cell types, providing valuable insights into its function and potential therapeutic implications. This antibody is a valuable tool for investigations into the molecular mechanisms of autophagy and intracellular trafficking, offering a deeper understanding of cellular processes that can impact disease development and progression.
Product Name:
ZFYVE16 Rabbit Polyclonal Antibody
SKU:
CAB7766
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ZFYVE16 (NP_055548.3).
Cytoplasm, Early endosome membrane, Peripheral membrane protein.
Calculated MW:
169kDa
Observed MW:
100kDa
This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9765
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse kidney, using ZFYVE16 antibody (CAB7766) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
