2'-O-methylcytidine/ Cm Monoclonal Antibody (CAB20693)
The 2'-O-methylcytidine/ Cm Monoclonal Antibody (CAB20693) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody specifically targets 2'-O-Methylcytidine (CM), a common modification found in various RNA molecules. By binding to CM, this antibody allows for the detection and analysis of CM-modified RNA in a variety of cell types and tissues.RNA modifications, such as 2'-O-Methylcytidine, play a crucial role in regulating gene expression and can impact various cellular processes. Research into RNA modifications has shown their importance in gene regulation, RNA stability, and protein translation.
This antibody is validated for use in ELISA, DB applications and has demonstrated reactivity against Species independent samples.
Product Name:
2'-O-methylcytidine/ Cm Monoclonal Antibody
SKU:
CAB20693
Size:
20μL, 100μL
Reactivity:
Species independent
Clone Number:
ARC50639
Conjugate:
Unconjugated
Immunogen:
Chemical compounds corresponding to 2'-O-methylcytidine/ Cm.
Sequence:
Cm c onju gate d to KLH
Tested Applications:
ELISADB
Recommended Dilution:
DB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Cm, 2'-O-methylcytidine, 2'-O-methylcytidine/ Cm
Observed MW:
Refertofigures
RNA methylation plays a significant regulatory role in various of physiological activities. 2'-O-methylcytidine (Cm) is one of the representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2'-oxygen position. 2’-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2'-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2’-O-methylcytidine was involved in plant stress responses.
Purification Method
Affinity purification
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
The 2'-O-methylcytidine(Cm) Rabbit mAb (CAB20693) are tested in Dot Blot against 2'-O-methylcytidine and unmodified cytidine.2'-O-methylcytidine ：Biotin-5'CGATAACCACTAGT(Cm)3'unmodified cytosine：Biotin-5'CGATAACCACTAGTC3'
