The ACAT2 Monoclonal Antibody (CAB1399) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, produced in rabbits, is highly specific to human ACAT2 and is ideal for use in Western blot applications. By binding to the ACAT2 protein, this antibody enables precise detection and analysis in various cell types, making it essential for research in lipid metabolism, atherosclerosis, and other related fields.ACAT2 is a key player in cholesterol esterification, the process by which cholesterol is stored in cells. Dysregulation of ACAT2 activity has been linked to conditions such as atherosclerosis and other cardiovascular diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
ACAT2 Monoclonal Antibody
SKU:
CAB1399
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2560
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ACAT2, acetyl-CoA acetyltransferase 2
Positive Sample:
HeLa, SW620, HepG2, Mouse liver, Mouse brain, Mouse kidney, Rat brain, Rat kidney
Cellular Localization:
Cytoplasm.
Calculated MW:
41kDa
Observed MW:
41kDa
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
39
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.