Anti-GITR antibody (DM80) Rabbit mAb (HDAB0067)

SKU:
HDAB0067
$756

Description

DescriptionThis gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Product nameAnti-GITR antibody (DM80) Rabbit mAb
SynonymsAITR, GITR, TNFRSF18, CD357
TypePrimary
Quantity100 µL
ShippingBlue Ice
AntigenGITR
ReactivityHuman
HostRabbit
ClonalityMonoclonal
CloneDM80
IsotypeRabbit IgG
ApplicationELISA,Flow Cyt
Immunogen substituteRecombinant human GITR (Gln266-Pro162) (HDPT0018) produced by using human HEK293 cells
PurificationPurified from cell culture supernatant by affinity chromatography
FormatLiquid
StorageStore at -20°C for 12 months (Avoid repeated freezing and thawing)
UsageResearch use only
Buffer50% Glycerol; PBS, pH 7.4; 0.1% BSA
Preservative0.1% Procline 300
ReconstitutionReconstitute with deionized water
Application AdviceELISA 1/5000-10000;Flow Cyt  1/100
Gene ID8784
Swiss-ProtQ9Y5U5
Molecular Weight26.0kDa
Assay Genie Related SKUsHDPT0018
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