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NUP88 Polyclonal Antibody (CAB20729)

SKU:
CAB20729
Product Type:
Antibody
Antibody Type:
Secondary Antibody
Host Species:
Goat
Isotype:
Fluorescein conjugated IgG
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NUP88 Polyclonal Antibody
SKU:CAB20729
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 502-741 of human NUP88 (NP_002523.2).
Sequence:SPPL LCTR EDVE VAES PLRV LAET PDSF EKHI RSIL QRSV ANPA FLKA SEKD IAPP PEEC LQLL SRAT QVFR EQYI LKQD LAKE EIQR RVKL LCDQ KKKQ LEDL SYCR EERK SLRE MAER LADK YEEA KEKQ EDIM NRMK KLLH SFHS ELPV LSDS ERDM KKEL QLIP DQLR HLGN AIKQ VTMK KDYQ QQKM EKVL SLPK PTII LSAY QRKC IQSI LKEE GEHI REMV KQIN DIRN HVNF
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:FADS4; NUP88
Positive Sample:NCI-H460,Jurkat,U-251MG,Rat testis
Conjugate:Unconjugated
Cellular Localization:cytosol, nuclear envelope, nuclear pore, nucleoplasm
Calculated MW:84kDa
Observed MW:88kDa

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:4927
Storage Buffer:Store at -20ā„ƒ. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using NUP88 antibody (CAB20729) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25Ī¼g per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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